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The Link Between Gut Health and Female Hormones

Writer: Caroline FarrellCaroline Farrell

Updated: Oct 10, 2024

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As women, our hormonal balance plays a crucial role in nearly every aspect of health, from mood and energy levels to skin health and metabolism. But did you know that your gut health is intricately connected to your hormone levels? This relationship, particularly between the gut and oestrogen, is governed by a complex system known as the estrobolome. In this article, we’ll explore the estrobolome, its role in hormone regulation, and how optimising gut health can help balance hormones.


What is the Estrobiome?


The estrobolome refers to a collection of gut bacteria that play a specific role in metabolising and regulating oestrogen, one of the primary sex hormones in women. These bacteria produce an enzyme known as β-glucuronidase, affects the levels of circulating oestrogen by reactivating or inactivating it. Essentially, the estrobolome determines how much oestrogen is excreted from the body and how much is reabsorbed back into the bloodstream. This balance is crucial. If your gut isn’t working optimally, it can lead to either too much or too little oestrogen in the body. Both imbalances can contribute to various health issues, such as:


  • Menopausal symptoms

  • PMS and menstrual irregularities

  • Endometriosis

  • Infertility

  • PCOS (polycystic ovarian syndrome)

  • Weight gain

  • Oestrogen dominance, which has been linked to an increased risk of certain cancers, particularly breast cancer.


Factors which Disrupt the Estrobiome


Several factors can disrupt gut health and, in turn, affect the estrobolome. These include:


  • Antibiotics: Frequent use of antibiotics can wipe out beneficial gut bacteria, including those involved in oestrogen metabolism.

  • Poor Diet: A diet high in processed foods, sugar, and unhealthy fats can encourage the growth of harmful bacteria, while lacking the fibre and nutrients necessary for a healthy microbiome.

  • Chronic Stress: Stress can weaken the gut barrier, leading to inflammation and dysbiosis.

  • Environmental Toxins: Certain chemicals, like BPA (found in plastics), can mimic oestrogen and interfere with hormone balance.

  • Hormonal Birth Control: Long-term use of hormonal contraceptives can impact gut bacteria and, over time, may lead to dysbiosis.


How to Support Your Estrobolome and Balance Hormones


Maintaining a healthy gut can significantly influence your hormonal health. Here are some evidence-based strategies to optimise gut health and support the estrobolome:


  • Eat a Fibre-Rich Diet: Fibre is essential for promoting a healthy gut. It feeds beneficial bacteria and supports digestion. Aim to include plenty of fruits, vegetables, legumes, and whole grains.

  • Eat Phytoestrogens: These are plant-based compounds that mimic oestrogen in the body, helping to balance female hormones. They can be found in soya products (like tofu, soya beans, and tempeh), flaxseeds, lentils, and chickpeas. The gut microbiome metabolises these phytoestrogens, making them more bioactive and effective for the body.

  • Include Probiotic Foods: Probiotics are beneficial bacteria that can help maintain a healthy microbiome. Fermented foods like yoghurt, kefir, sauerkraut, and kimchi are excellent sources of probiotics. You may also like to consider a supplement.

  • Reduce exposure to environmental toxins: Limiting exposure to toxins like BPA (commonly found in plastics) and hormone-disrupting chemicals in cosmetics can protect both gut health and hormone balance. These substances can mimic natural hormones, disrupting the microbiome and contributing to hormonal imbalances.

  • Limit Processed Foods and Sugar: Highly processed foods and refined sugars can contribute to gut dysbiosis, creating an imbalance of harmful bacteria. Minimising these foods helps your gut thrive and supports oestrogen regulation.

  • Manage Stress: Chronic stress negatively impacts gut health and hormone balance. Incorporate stress-reducing activities like yoga, meditation, or regular physical exercise into your routine to keep your gut and hormones in sync.



Conclusion


The relationship between gut health and female hormones is both complex and fascinating, with the estrobolome playing a pivotal role in managing oestrogen levels. Supporting your gut microbiome through a balanced diet, managing stress, and living a healthy lifestyle can help regulate hormones and improve your overall health. Always consult with a healthcare professional, such as a nutritionist for personalised advice and recommendations.







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